“Every good mathematician is at least half a philosopher, and every good philosopher is at least half a mathematician.”
—Gottlob Frege
I absolutely love this quote :) soo true!
(Source: molotovpanini)
The Life-Cycle of Spirochaeta duttoni, as elucidated by William Boog Leishman
Fig 1-6. General character of organism
Fig 6-8. Transverse division
Fig 9. Longitudinal division
Fig 10-11. Unknown method reproduction, thought to be conjugation
Fig 12. Coiled form in peripheral blood
Fig 13. Swollen form in liver
Fig 14-15. Skein-like forms in the spleen
Fig 16. Encysted formSpirochetes such as Spirochaeta duttoni and Trepanoma pallidum pallidum (syphilis) were originally grouped with other eukaryotic parasitic organisms such as protozoa, because their methods of reproduction (both longitudinal and transverse division) made discerning their true nature confusing at first.
All spirochetes are now known to be Gram-negative helically-coiled bacteria. The species “Spirochaeta duttoni” (now Borrelia duttoni) causes African tick fever, which causes general muscle pain, fever, chills, nausea, and a generalized rash. The bacteria has the ability to change its surface proteins to evade the immune system for some time, and as such often relapses after initial treatment.
[Human Parasitology. Damaso Rivas, 1920.]
Treponema pallidum manifestations
Top Right: Treponema pallidum pallidum - Venereal Syphilis
Top Left: Treponema pallidum pertenue - Gangosa (Yaws)
Bottom: Treponema pallidum pertenue - Frambosia (Yaws)The spirochete Trepanoma pallidum has several subspecies that affect man, though only T. p. pallidum (syphilis) is transmitted via sexual contact. The other common disease caused by the spirochete is yaws. This tropical disease was largely ignored for most of the 20th century, as it rarely affects affluent countries.
Its course of infection can sometimes resemble syphilis, with the ulcerating gummas, multiple stages of infection, and destruction of tissues, but it is transmitted via skin-to-skin contact, and is not known to cross the placental membrane (meaning that, unlike syphilis, babies cannot be born with it). The tissue destruction within the muscles, skin, and bones, is a feature of tertiary yaws, which arises years after the initial infection. When the facial tissues are destroyed, the disease is commonly called gangosa.
[A Treatise on the Diseases of the Skin. Henry W. Stelwagon, 1923]
[Human Parasitology. Damaso Rivas, 1920.]
“This illustration shows a cross-section of a small portion of an Escherichia coli cell. The cell wall, with two concentric membranes studded with transmembrane proteins, is shown in green. A large flagellar motor crosses the entire wall, turning the flagellum that extends upwards from the surface. The cytoplasmic area is colored blue and purple. The large purple molecules are ribosomes and the small, L-shaped maroon molecules are tRNA, and the white strands are mRNA. Enzymes are shown in blue. The nucleoid region is shown in yellow and orange, with the long DNA circle shown in yellow, wrapped around HU protein (bacterial nucleosomes). In the center of the nucleoid region shown here, you might find a replication fork, with DNA polymerase (in red-orange) replicating new DNA.”
© David S. Goodsell 1999.
Desmoplastic medulloblastoma with extensive nodualrity. This tumor was removed from a 3-year old female with an enhancing posterior fossa tumor.